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 Osteoallograft® Orthomix®
 Osteoallograft® Periomix®
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Osteoallograft® Periomix® (Equine)
 

Product Description
Indications
Veterinarian and Patient Benefits
Product Specifications
Support Materials
Clinical References


Product Description

Osteoallograft® Periomix® is natural, real bone allograft designed specifically for veterinary dentistry. It consists of osteoinductive Demineralized Bone Matrix (DBM) and osteoconductive cancellous bone chips. Using bone allograft in periodontics allows you to restore periodontium to save teeth instead of extracting them. It also allows you to effectively restore bone in extraction sites to support good oral and systemic health and to prevent fracture of the mandible. And because it not only provides osteoconductive scaffold but also osteoinductive growth factors (BMPs), you will achieve faster and stronger bone healing compared with using bone substitutes. 1-4

The demineralization of allograft allows for immediate access to the growth factors (BMPs) inherent in allograft bone when it is placed into the surgery site. This results in an immediate beginning of the healing process and helps to make allograft as effective as autograft. 5-6


Osteoallograft® Periomix® is professional-grade allograft:

Processed aseptically meeting USP guidelines for sterility

Acellular and processed by methods that reduce immunogenicity, which eliminates concerns about immune reactions and the need for any type of patient matching

Our production practices are GMP and Good Tissue Practices compliant and modeled after human tissue banking standards

Our stringent Quality Assurance Program provides confidence and consistency in our products


Indications

Use Osteoallograft® Periomix® for:
Horizontal and vertical bone loss
Tooth extractions
Filling mandibular bone cysts
Fracture of the mandible
Any other void filling or bone augmentation procedure that would benefit from grafting


Veterinarian and Patient Benefits

Up to 34% of horses of all ages experience some level of periodontal disease and up to 60% of horses 13 years of age and older suffer from severe periodontal disease.7 Because of an increased understanding of systemic effects as well as morbidity and pain caused by periodontal disease, periodontics is emerging as a brand new field in equine dentistry.

Here is why small animal veterinarians and human periodontists use bone allograft in periodontics:

After Extractions:
Applying bone allograft after tooth extractions quickly restores bone in extractions sites. 1-8 And due to its osteoinductive growth factors, natural allograft restores bone faster and stronger than bone substitutes. 1-4 To see a Grafting Options Comparison Chart, click here.

Why restore bone in extraction sites:

Unfilled extraction sites can harbor bacteria and enable progression of periodontal disease, which in turn can cause further bone and tooth loss and can have systemic effects

Leaving deep extraction sites unfilled can result in weakened jaw bone or a pathologic fracture


For Tooth Preservation:
Applying bone allograft around exposed roots rapidly restores bone lost due to periodontal disease and results in reconstruction of the attachment apparatus thus preserving teeth. 1-2, 8

Why restore the attachment apparatus:

Allows you to preserve teeth rather than extracting them or risking exfoliation. Missing teeth result in a lack of stimulation of the underlying bone structure, which can result in bone loss.

If exposed roots are left untreated, periodontal disease and bone loss will continue

Bone loss can result in exfoliation teeth, weakened bone, or a pathologic fracture

Periodontal disease has systemic effects

Exposed roots are likely to be painful


Product Specifications

Product Name: Periomix®
  Orthomix-Fine
Particle Size: Demineralized Bone Matrix with cancellous
chips < 4.0 mm
Indications: Tooth extractions
Bone loss
Fractured mandible
Filling mandibular cysts
Preservation: Freeze-Dried
Volumes Available: 6 cc
15 cc coming soon
To use our Online Order Form, click here



Support Materials

Osteoallograft Periomix Flyer (PDF: 694 KB)
Frequently Asked Questions (PDF: 111 KB)
Literature List with Excerpts (PDF: 173 KB)
A Word from the Director (PDF: 233 KB)
Pricelist (PDF: 734 KB)
Fax Order Form (PDF: 264 KB)
Online Order Form



Clinical References


1.
Carranza FA, Takei HH, Cochran DL.  Reconstructive periodontal surgery.  in: Carranza's Clinical Periodontology, 10th ed. Carranza FA, et al., eds., Saunders Elsevier, St. Louis, Mo., pp. 972-980, 2006.
2.
Mellonig JT.  Freeze-dried bone allografts in periodontal reconstructive surgery.  Dent Clin North Am: Reconstructive Periodontics.  July 35(3): 505-520, 1991.
3.
Hall EE, Meffert RM, Hermann JS, Mellonig JT, Cochran DL.  Comparison of bioactive glass to demineralized freeze-dried bone allograft in the treatment of intrabony defects around implants in the canine mandible.  J Periodontol.  May 70(5): 526-535, 1999.
4.
Meadows CL, Gher ME, Quintero G, Lafferty TA.  A comparison of polylactic acid granules and decalcified freeze-dried bone allograft in human periodontal osseous defects.  J Periodontol. 64: 103-109, 1993.
5.
Samartzis D, Shen FH, Matthews DK, Yoon ST, Goldberg EJ, An HS. Comparison of allograft to autograft in multilevel anterior cervical discectomy and fusion with rigid plate fixation. Spine J. Nov-Dec 3(6): 451-9, 2003.
6.
Piotrowski M, Pankowski R, Luczkiewicz P, Markowicz A. A comparison of the effect of autogenous vs. frozen homogenous grafts on the healing of non-union of forearm bones. Ortop Traumatol Rehabil. 10(2): 146-51, 2008.
7.
Klugh DO. Equine periodontal disease. Clinical Techniques in Equine Practice. 4(2): 135-147, 2005.
8.
Mellonig, JT.  Bone allografts in periodontal therapy.  Clin Orthop Relat Res.  Mar (324): 116-125, 1996.


To see more references for use of bone graft in periodontics, click here >>



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Chart

Click on image to see a Grafting Options Comparison Chart


Klugh DO. Equine
periodontal disease.
Clinical Techniques in
Equine Practice. 4(2): 135-147, 2005.

Click here to see more references >
 
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