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Product Description
Indications
Veterinarian and Patient Benefits
Product Specifications
Usage Imagery
Support Materials
Clinical References
Product Description
Osteoallograft® Orthomix® is natural, real bone allograft designed specifically for veterinary use. It consists of osteoinductive Demineralized Bone Matrix (DBM) and osteoconductive cancellous bone chips. Using bone allograft allows you to avoid autograft procurement and associated morbidity risks. Also, because it not only provides osteoconductive scaffold but also native, osteoinductive growth factors (BMPs), you will achieve faster and stronger bone healing compared with using bone substitutes. 1
The demineralization of allograft during tissue processing allows for immediate access to the growth factors (BMPs) inherent in natural bone when it is placed into the surgery site. This results in an immediate beginning of the healing process and helps to make allograft as effective as autograft. 2-4
Osteoallograft® Orthomix® is professional-grade allograft:
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Processed aseptically meeting USP guidelines for sterility |
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Acellular and processed by methods that reduce immunogenicity, which eliminates concerns about immune reactions and the need for any type of patient matching. |
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Our production practices are GMP and Good Tissue Practices compliant and modeled after human tissue banking standards |
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Our stringent Quality Assurance Program provides confidence and consistency in our products |
Indications
| Use Osteoallograft® Orthomix® for: |
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Fracture repair |
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Mal- or non-union cases |
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Arthrodesis procedures |
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Bone loss |
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TTAs and TPLOs 2,5 |
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Any other application where bone graft is needed |
Veterinarian and Patient Benefits
| Why graft: |
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Bone will heal faster when voids are filled with bone graft, because it provides osteoconductive scaffold for host bone to grow on and native, osteoinductive BMPs that attract osteoblasts to the site. Even when there are no voids, bone graft provides these same advantages. 2,6,7 |
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Faster healing not only gets your patients back to normal activity faster it also increases the chances of a successful healing outcome 2,6,7 |
| Why use allograft: |
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Reduces your OR time and cost, because it allows you to skip autograft harvesting 8 |
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Eliminates morbidity risks associated with the collection of bone autograft. Studies show a morbidity rate of over 25% in humans 9 |
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In many cases, allows you to use more bone graft than you can procure from the patient. Allograft can also be used to augment insufficient quantities of autograft. |
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Studies show that allografts are as effective as autograft in bone healing 2-4 |
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Achieves faster and stronger bone healing than bone substitutes due to osteoinductive growth factors (BMPs) inherent in natural bone.1 To see Grafting Options Comparison Chart, click here. |
Available Product Types
| Product Name: |
Orthomix® - Standard |
Orthomix® - Fine |
Orthomix® - Ultra Fine |
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| Particle Size: |
Demineralized Bone Matrix with cancellous
chips < 4.0 mm |
Demineralized Bone Matrix with cancellous
chips < 2.3 mm |
Demineralized Bone Matrix with cancellous
chips < 0.7 mm |
| Indications: |
Large fracture voids
Large mal- or non unions
Large bone loss cases |
Fracture voids
Mal- or non-unions
Bone loss cases
TPLOs and TTAs |
Fractures with no voids
Small breeds
Arthrodeses
Hip implants |
| Preservation: |
Freeze-Dried
or Frozen |
Freeze-Dried
or Frozen |
Freeze-Dried |
| Volumes Available: |
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| Feline: |
0.5 cc |
| Canine: |
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1 cc |
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2 cc |
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3 cc |
| 4 cc |
(frozen only) |
| 5 cc |
(frozen only) |
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| To use our Online Order Form, click here |
Usage Imagery
Osteoallograft® Orthomix® is easy to use:
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Rehydrate graft with saline.
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Mix Osteoallograft® Orthomix® with patient blood or bone marrow. |
Apply to surgical site. |
When working in a vascular site, grafts can be applied directly out of the syringe. |
Support Materials
Osteoallograft Orthomix Brochure (PDF: 738 KB)
Osteoallograft Orthomix Case Study with Shaft Section (PDF: 578 KB)
Frequently Asked Questions (PDF: 111 KB)
Literature List with Excerpts (PDF: 173 KB)
A Word from the Director (PDF: 233 KB)
Pricelist (PDF: 734 KB)
Fax Order Form (PDF: 415 KB)
Online Order Form
Clinical References
| 1. |
Griffon DJ, Dunlop DG, Howie CR, Gilchrist T, Salter DM, Healy DM. Early dissolution of a morsellised impacted silicate-free bioactive glass in metaphyseal defects. J Biomed Mater Res (Applied Biomater). 58(6):638-644, 2001. |
| 2. |
Hoffer M, Griffon D, Schaeffer D, Johnson A, Thomas M. Clinical applications of demineralized bone matrix: A retrospective and case-matched study of 75 dogs. Vet Surg. 37:639-647, 2008. |
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| 9. |
Younger EM, Chapman MW. Morbidity at bone graft donor sites. J Orthop Trauma. 3(3):192-195, 1989. |
To see more references for use of bone graft in orthopedics, click here >>

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