Shafts and whole bones are tissues that are generally not possible to obtain as autografts. They are most commonly used for replacement of large bone sections affected by osteosarcoma in an effort to avoid amputation (limb-sparing procedure). They are also used in other situations where there is significant bone loss. These grafts are aseptically procured and processed. The periosteal and soft tissues are thoroughly removed and, if accessible, the marrow compartment is cleaned and lavaged. They are treated with antibiotics, rinsed, measured directly, cultured and packaged. We can also create custom made grafts for specific applications.