Membrane Types | Indications | Benefits | Case Studies | Brochure | References
Membranes are flexible grafts that have a variety of applications. They are available in different forms: Ossiflex™ (flexible bone membranes) and Fascia (fascia lata grafts). Each has different handling characteristics, but all serve to provide a membrane barrier and guide. All VTS membrane products are biocompatible and biodegradable and ultimately are replaced by the patient’s own tissues, no removal is necessary. They can be sutured into place.In dentistry they are primarily used as a barrier for Guided Tissue/Bone Regeneration purposes to prevent premature epithelial and fibroblast in-growth into areas of bone healing. They can also be used to bridge bone defects (e.g., cleft palates), close fistulae (e.g. oro-nasal fistulae).
In orthopedics, fascia grafts can be used to bolster partially ruptured tendons or patch dural or rotator cuff defects.
Membrane Types
Ossiflex™ Bone Membranes from VTS are thin, flexible sheets made of natural demineralized cortical bone. These are thicker than the other membranes, and being made of cortical bone provide a natural surface compatible with bony integration as well as epithelialization.
Size 1:
1.0 x 1.0 cm
(Freeze-Dried)
1.0 x 1.0 cm
(Freeze-Dried)
Indications:
GTR on small breeds, small cranio-maxillo facial defects, small canal openings
GTR on small breeds, small cranio-maxillo facial defects, small canal openings
Size 2:
1.0 x 1.5 cm
(Freeze-Dried)
1.0 x 1.5 cm
(Freeze-Dried)
Indications:
GTR on medium breeds, medium cranio-maxillo facial defects, medium canal openings
GTR on medium breeds, medium cranio-maxillo facial defects, medium canal openings
Size 3:
1.5 x 2.0 cm
(Freeze-Dried)
1.5 x 2.0 cm
(Freeze-Dried)
Indications:
GTR on large breeds, large cranio-maxillo-facial defects, large canal openings
GTR on large breeds, large cranio-maxillo-facial defects, large canal openings
Size 3L:
1.5 x 4.0 cm
(Freeze-Dried)
1.5 x 4.0 cm
(Freeze-Dried)
Indications:
Long, narrow cranio-maxillo-facial defects
Long, narrow cranio-maxillo-facial defects
Size 4:
2.0 x 3.0 cm
(Freeze-Dried)
2.0 x 3.0 cm
(Freeze-Dried)
Indications:
Very large cranio-maxillo-facial defects, fracture bridging
Very large cranio-maxillo-facial defects, fracture bridging
Size 5:
3.0 x 3.5 cm
(Freeze-Dried)
3.0 x 3.5 cm
(Freeze-Dried)
Indications:
Very large cranio-maxillo-facial defects, fracture bridging
Very large cranio-maxillo-facial defects, fracture bridging
Indications
Use Ossiflex™ Bone Membranes for:
- Guided Tissue Regeneration (GTR) 1-6
- Oronasal Fistulas
- Cleft Palates
- Cranio Facial Defects
- Fracture Bridging
- Mandibular Canal Protection
Veterinarian and Patient Benefits
Why use Ossiflex™:
- Guided Tissue Regeneration
Placing a membrane between bone graft and soft tissue avoids premature soft tissue in-growth. 1-6 - Oronasal Fistulas
While thin and flexible, Ossiflex™ Bone Membranes are strong enough to keep food particles from traveling through oronasal defects. - Cleft Palates and Cranio-Facial Defects
Ossiflex™ Bone Membranes are also ideal for treating cranio-maxillo-facial defects. For example, they can be used to support mucoperiosteal advancement flaps for closure of palatal defects. - Fracture Bridging
Ossiflex™ Bone Membranes can be wrapped around mandibular fractures to support healing. - Mandibular Canal Protection
Ossiflex™ Bone Membranes can be placed over open mandibular canals to keep growing tissue from impinging the nerve.
Case Studies
- Periomix & Membrane Case Studies: Odontoclastic Resorptive Lesions, Vertical & Horizontal Bone Loss, Alveolar Osteitis, Deep pocket Periodontal Disease (Mele)
- Ossiflex Bone Membrane: Closure of Oronasal Fistula (Mele, “Riley”)
- Ossiflex Bone Membrane: Closure of Large Palatal Defect (Yee, “Champ”)
- Ossiflex Case Studies: Maxilla Guided Bone Regeneration (GBR), Mandible Guided Tissue Regeneration (GTR) (Mele)
- Ossiflex Bone Membrane: Maxillary Cyst (Dentigerous) (Mele, “Annie”)
- Ossiflex Bone Membrane: Palate Repair: Penetrating Trauma and Caudal Fracture (Beckman, “Arnold”)
- VTS Fascia: Oronasal Fistula Repair (Battig, “Tinkerbell)
- Periomix Case Studies: Dental Implant & Large Extraction (Periomix + Block + Ossiflex) (Mele)
Brochure
References
- Fugazzotto PA. The use of demineralized laminar bone sheets in guided bone regeneration procedures: report of three cases. Int J Oral Maxillofac Implants. 11: 239-244, 1995.
- Rosenquist B, Ahmed M. The immediate replacement of teeth by dental implants using homologous bone membranes to seal the sockets: clinical and radiographic findings. Clin Oral Impl Res. 11: 572–582, 2000.
- Scott TA, Towle HJ, Assad DA, Nicoll BK. Comparison of bioabsorbable laminar bone membrane and non-resorbable ePTFE membrane in mandibular furcations. J Periodontal. 68: 679-686, 1997.
- Rankow, Henry J, Krasner, Paul R. Endodontic applications of guided tissue regeneration in endodontic surgery. Oral Health. 86(12): 33, 1996.
- Mundell RD, Mooney MP, Siegel MI, Losken A. Osseous guided tissue regeneration using a collagen barrier membrane. J Oral Maxillofac Surg. 51: 1004-1012, 1993.
- Majzoub Z, Cordioli G, Aramouni PK, Vigolo P, Piattelli A. Guided bone regeneration using demineralized laminar bone sheets versus GTAM membranes in the treatment of implant-associated defects. A clinical and histological study. Clin Oral Implants Res. 10:406-414, 1999.
- Cox CL, Hunt GB, Cadier MM. Repair of oronasal fistulae using auricular cartilage grafts in five cats. Veterinary Surgery 36: 164-169, 2007.
- Soukup JW, Synder CJ, Gengler WR. Free auricular cartilage autograft for repair of an oronasal fistula in a dog. J Vet Dent. 26(2): 86-95, 2009.
- Duskova M, Leamerova E, Sosna B, Gojis O. Guided tissue regeneration, barrier membranes and reconstruction of the cleft maxillary alveolus. J Craniofac Surg. 17(6):1153-1160, 2006.
- Scott JK, Webb RM, Flood TR. Premaxillary osteotomy and guided tissue regeneration in secondary bone grafting in children with bilateral cleft lip and palate. Cleft Palate Craniofac J. 44(5): 469-475, 2007.
- Le BT, Woo I. Alveolar cleft repair in adults using guided bone regeneration with mineralized allograft for dental implant site development: a report of 2 cases. J Oral Maxillofac Surg. 67: 1716-1722, 2009.
- Retzepi M, Donos N. Guided bone regeneration: biological principle and therapeutic applications. Clin Oral Impl Res. 21: 567-576, 2009.
- Reiser GM, Manwaring JD, Damoulis PD. Clinical significance of the structural integrity of the superior aspect of the mandibular canal. J Periodontal. 75(2): 322-326, 2004.
Fascia from VTS are processed and freeze-dried fascia lata allografts. Fascia is a natural collagen scaffold that allows for integration with the host tissues; cellular ingrowth organizes along the native fibers inherent in fascia. During the integration phase it provides a barrier for GTR procedures. It is thinner and somewhat more flexible than the Ossiflex Bone Membranes.
Fascia Lata
2.0 x 3.0 cm or 3.0 x 5.0 cm sheets (freeze-dried, minimum dimensions)
2.0 x 3.0 cm or 3.0 x 5.0 cm sheets (freeze-dried, minimum dimensions)
Indications:
Can be used wherever biological material is needed
Can be used wherever biological material is needed
Indications
Use Fascia for:
- Guided Tissue Regeneration (GTR) 1-6
- Oronasal Fistulas
- Cleft Palates
- Cranio Facial Defects
Veterinarian and Patient Benefits
Why use Fascia:
- Guided Tissue Regeneration
Placing a membrane between bone graft and soft tissue avoids premature soft tissue in-growth. 1-6 - Oronasal Fistulas
While thin and flexible, Fascia are strong enough to keep food particles from traveling through oronasal defects. - Cleft Palates and Cranio-Facial Defects
Fascia are also ideal for treating cranio-maxillo-facial defects. For example, they can be used to support mucoperiosteal advancement flaps for closure of palatal defects.
Case Studies
References
- Rankow, Henry J, Krasner, Paul R. Endodontic applications of guided tissue regeneration in endodontic surgery. Oral Health. 86(12): 33, 1996.
- Cox CL, Hunt GB, Cadier MM. Repair of oronasal fistulae using auricular cartilage grafts in five cats. Veterinary Surgery 36: 164-169, 2007.
- Soukup JW, Synder CJ, Gengler WR. Free auricular cartilage autograft for repair of an oronasal fistula in a dog. J Vet Dent. 26(2): 86-95, 2009.
- Duskova M, Leamerova E, Sosna B, Gojis O. Guided tissue regeneration, barrier membranes and reconstruction of the cleft maxillary alveolus. J Craniofac Surg. 17(6):1153-1160, 2006.
- Retzepi M, Donos N. Guided bone regeneration: biological principle and therapeutic applications. Clin Oral Impl Res. 21: 567-576, 2009.